Born: February 10, 1690, Spitalfields, London, England.
Died: November 6, 1739, Tiverton, Devon, England.
Buried: St. George churchyard, Tiverton, Devon, England.

Samuel was the eldest son of Samuel Wesley and Susanna Annesley, brother of John and Charles Wesley, and husband of Ursula Berry.
He was trained at Westminster School and Christ Church, Oxford. He became usher at Westminster.
He taught at Blundell’s School, and in 1732 became head master at the Tiverton Free School (now Tiverton High School).
He was a close friend of Bishop Atterbury, and was one of the promoters of the first infirmary set up at Westminster for the sick in 1719.