Holzworth was educated at Trinity State College, Indiana. He studied organ with Professor Rutenberg in New York, and Professor Christian in Chicago, Illinois; voice with Professor William Miles and K. M. Spencer; and theory with Professor Hermon Watt and Rosseter Cole.
Holzworth taught piano, organ, and theory for ten years, privately, and in the Music Department of Tri-State College (now Trine University), Angola, Indiana.
A tenor, he was he was also an accomplished concert performer, and experienced in training chorus and quartette choirs.
He joined the music department of Moody Bible Institute, Chicago, Illinois, around 1918.
We speculate he is Alfred Holzworth (1882–1972), buried in Lindenwood Cemetery, Fort Wayne, Indiana.
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