Born: April 18, 1807, Colrain, Massachusetts.
Died: October 6, 1886, Waimea, Hawaii.
Buried: Imiola Church, Waimea, Hawaii.
Lorenzo was the son of Jerre Lyons and Mary Richards. He married twice, to Lucia Smith and Betsey Curtis.
He was ordained a Congregational minister at Auburn Seminary in 1831. Sailing from New Bedford, Massachusetts, in November 1831, he arrived in the South Kohala district of the island of Hawaii in 1832.
He spent the rest of his life dedicated to native Hawaiians. Fluent in the Hawaiian language, he composed many poems and hymns. His Waimea parish eventually included the districts of Kohala and Hamakua, making it the largest mission station in Hawaii.
During his tenure, he was responsible for erecting 14 churches. He also served as district postmaster from 1858 until his death.